After being drafted in 2005, Canty split time with Greg Ellis at right defensive end and led all defensive linemen with 43 tackles. He was also second on the team with five tackles behind the line and tied for fourth on the club with 2.5 sacks. Canty took to the field in the season opener at San Diego (9/11) and recorded his first NFL tackle along with a quarterback pressure. Against Washington (9/19) he added his first career sack with a third-quarter takedown of Mark Brunell. He was third on the team, tops among linemen with a season-high six tackles at Oakland (10/2). He also added half a sack and a tackle for a loss.
Canty had two tackles against Philadelphia (10/9) as the defense limited the Eagles to 129 total yards, including just 19 on the ground - the fourth lowest rushing total in club history. At Seattle (10/23) he recorded two tackles as the NFL's top ranked offense entering the game was limited to 289 total yards, 118 below their season average, and one touchdown. Shaun Alexander, the NFL leading rusher entering the game at 119 yards-per-game (5.5 avg.), was limited to 61 yards on 21 carries (2.9 avg.).